Phellodendron bark extract Berberine HCL Powder
Products Description
Berberine HCl powder from Phellodendron amurense bark extract is a highly purified botanical ingredient standardized to 97% or higher. Extracted from the bark of the Phellodendron amurense tree, our berberine HCl powder is a fine yellow crystalline powder with excellent water solubility, making it ideal for use in dietary supplements, blood sugar support formulations, and herbal health products. Berberine HCl has anti-inflammatory, antimicrobial, and metabolic modulatory properties that have been validated in numerous clinical and preclinical studies.
With the growing global interest in natural metabolic support, berberine HCl has become one of the most sought-after botanical active ingredients, especially in North America and Europe, where demand for blood sugar management and weight control supplements is growing.
The uniqueness of our berberine HCl product lies in our proprietary fermentation-free extraction process, which consistently yields a high purity product (≥97%) while maintaining ultra-low heavy metal content—<1.0 ppm for lead and <0.5 ppm for arsenic—well below industry standards.
Why choose our Phellodendron Bark Extract Berberine HCL Powder?
1. High Active Content – ≥97% Berberine HCL
We standardize our product to ≥97% purity, tested by HPLC.Lot-to-lot variation is tightly controlled within ±1%, ensuring formulation accuracy for capsules, tablets, or sachets.
2. 100% Botanical Source – No Fermentation or Synthetics
Our Berberine HCL is extracted exclusively from wild-harvested Phellodendron bark.No GMO materials, synthetic fermentation residues, or artificial fillers—meets clean-label and natural origin standards.
3. Clean Extraction – No Harsh Solvents
Extraction uses only ethanol and purified water, without methanol or acetone.Fully compliant with EU food-grade standards and preferred by nutraceutical brands focused on safety.
4.Low Heavy Metals
Our Berberine HCL Powder consistently tests below 1.0 ppm lead, 0.5 ppm arsenic, and 0.5 ppm cadmium (ICP-MS), exceeding pharmacopeia safety standards and minimizing formulation risks.
01
COA
| Item | Specification | Result |
| Product Name | Phellodendron Bark Extract Berberine HCL Powder | Complies |
| Appearance | Yellow crystalline powder | Complies |
| Odor & Taste | Characteristic | Complies |
| Assay (Berberine HCL) | ≥97.0% (HPLC) | 97.42% |
| Loss on Drying | ≤2.0% | 0.89% |
| Ash | ≤1.0% | 0.42% |
| Bulk Density | 0.45–0.75 g/mL | 0.59 g/mL |
| Tapped Density | 0.60–0.90 g/mL | 0.78 g/mL |
| Solubility | Soluble in water & ethanol | Complies |
| Particle Size | 95% pass 80 mesh | Complies |
| Heavy Metals | ≤10 ppm | Complies |
| Lead (Pb) | ≤1.0 ppm (ICP-MS) | 0.41 ppm |
| Arsenic (As) | ≤1.0 ppm (ICP-MS) | 0.28 ppm |
| Cadmium (Cd) | ≤1.0 ppm (ICP-MS) | 0.17 ppm |
| Mercury (Hg) | ≤0.1 ppm (ICP-MS) | Not detected |
| Total Plate Count | ≤1,000 CFU/g | <100 CFU/g |
| Yeast & Mold | ≤100 CFU/g | <10 CFU/g |
| E. coli | Negative | Negative |
| Salmonella | Negative | Negative |
| Staphylococcus aureus | Negative | Negative |
What is the application of berberine?
1. Dietary Supplements
Widely used in capsule and tablet formats for general wellness and metabolic support.
2. Blood Sugar Support Formulas
Incorporated into formulas targeting insulin sensitivity and glucose regulation.
3. Weight Management Products
Commonly found in fat metabolism and appetite control blends.
4. Gut Health Solutions
Supports microbiome balance and helps reduce inflammation in the digestive tract.
5. Traditional Herbal Blends
Used in combination with other Eastern herbs like Coptis and Scutellaria.
6. Skin Health Capsules
Employed for its anti-inflammatory and antibacterial properties, especially in acne-targeted products.
7. Pet Health Additives
Added to animal supplements for antimicrobial and gut-supportive functions.
Recommended Usage & Dosage
1.Capsules/Tablets:
500–1500 mg per day, divided into 2–3 doses
2.Functional Blends:
0.5–2% inclusion rate depending on formulation goals
3.Topical Formulations:
Not commonly used due to low dermal absorption, but 0.1–0.5% may be explored under clinical supervision
Note: Usage should align with local regulatory guidelines (e.g., EFSA, FDA, etc.)
Frequently Asked Questions (FAQ)
1. Can it be combined with Metformin or other medications?
Many use Berberine as a natural Metformin alternative. However, co-usage should be done under medical guidance due to potential additive effects on blood sugar.
2. Is Berberine natural or synthetic?
Our Berberine HCL is 100% natural, extracted from Phellodendron amurense bark through a water-alcohol process — not synthetically manufactured.
3. What makes high-purity Berberine better?
Standardized purity (≥97%) ensures consistent dosing, higher bioavailability, and fewer unwanted alkaloid contaminants — critical for formulator trust and product stability.
Trusted Supplier of Berberine HCL Powder Bulk and OEM Orders
As a reliable supplier of Phellodendron Bark Extract Berberine HCL Powder, we offer bulk orders and custom solutions. Our product meets high-quality standards, ensuring consistency and safety for your business.For inquiries or orders, contact us at info@btncbio.com















