Fisetin Powder
PrFisetin Powder – Natural Cotinus Coggygria Extract for Longevity
Our Fisetin Powder, also known as 3,3′,4′,7-Tetrahydroxyflavone, is primarily extracted from Rhus verniciflua (the lacquer tree), a natural source renowned for its high flavonoid content. The main bioactive compound, fisetin, is a polyphenolic flavonol with strong antioxidant, anti-inflammatory, and senolytic properties. Scientific studies suggest that fisetin can help clear senescent cells, support cellular regeneration, reduce oxidative stress, and improve markers associated with aging and metabolic health. Minor flavonoids naturally present in our extract may act synergistically, further enhancing its biological activity.
The global demand for fisetin is growing rapidly, especially in the nutraceutical, dietary supplement, and functional cosmetic markets. Consumers and formulators increasingly seek plant-based, high-purity extracts that offer consistent bioactivity and traceable sourcing. Market analyses indicate that premium fisetin ingredients derived from Cotinus Coggygria are highly valued for their natural origin, stability, and reproducible concentration, making them more appealing than synthetic alternatives.
What differentiates our Rhus verniciflua Fisetin Powder is the combination of natural efficacy, standardized extraction, and tailored OEM/ODM capabilities. We ensure a controlled fisetin concentration, uniform powder quality, and flexibility in customized formulations and packaging, allowing brands to seamlessly incorporate it into capsules, tablets, functional beverages, or skincare products. Our stringent quality assurance and traceable sourcing offer a level of reliability and reproducibility that many competitors cannot provide, making our product not just an ingredient, but a strategic solution for premium formulations.
Why our fisetin powder?
1. High purity:
Our fisetin powder is over 98% pure, as verified by HPLC testing. Through low heat concentration and vacuum pressure processes, we maintain the integrity of the active compound, ensuring maximum efficacy for nutraceutical, pharmaceutical and dietary applications.
2. Premium raw materials:
Our fisetin is sourced from the highest quality Rhus cotinus L. (smoke tree), from sustainably grown, pesticide-free plants, ensuring a pure and potent product.
3. Comprehensive quality control:
We perform rigorous testing for heavy metals, residual solvents, pesticides and microbial contaminants to ensure our fisetin meets the highest safety and quality standards.
Manufacturing process chart

COA
| Test Item | Specification | Test Method | Results |
| Appearance | Yellow Fine Powder | Visual Inspection | Complies |
| Purity (HPLC) | ≥ 95% | HPLC | 98.5% |
| Loss on Drying | ≤ 1% | Drying at 105°C for 2 hours | 0.2% |
| Ash Content | ≤ 1% | Incineration at 600°C | 0.3% |
| Heavy Metals | ≤ 10 ppm | Atomic Absorption Spectroscopy (AAS) | <5 ppm |
| Arsenic (As) | ≤ 1 ppm | AAS | <0.5 ppm |
| Lead (Pb) | ≤ 1 ppm | AAS | <0.3 ppm |
| Cadmium (Cd) | ≤ 0.1 ppm | AAS | <0.1 ppm |
| Mercury (Hg) | ≤ 0.1 ppm | AAS | <0.05 ppm |
| Total Microbial Count | ≤ 1000 CFU/g | Plate Count Method | 350 CFU/g |
| Yeast & Mold | ≤ 100 CFU/g | Plate Count Method | 50 CFU/g |
| E. Coli | Negative | PCR/Colony Count | Negative |
| Salmonella | Negative | PCR/Colony Count | Negative |
| Solubility | Soluble in Water and Ethanol | Visual Test | Complies |
| Particle Size | 100% pass 80 mesh | Sieve Analysis | Complies |
| Storage Conditions | Store in a cool, dry place | - | Complies |
Common Applications of Fisetin Powder
1.Anti-aging Supplements
Known for its antioxidant properties, fisetin helps reduce oxidative stress and support skin health.
2.Brain Health
Fisetin supports memory and cognitive function with its neuroprotective effects.
3.Skin Care
Its antioxidant and anti-inflammatory properties help reduce wrinkles and promote skin health.
4.Inflammation Management
Fisetin aids in reducing inflammation and supporting joint health.
Recommended Dosages of Fisetin Powder
1. General Health: 100-250 mg/day
2. Anti-aging: 200-500 mg/day
3. Brain Health: 200-400 mg/day
4. Skin Care: 100-200 mg/day
Tips: Dosage may vary based on individual health conditions and product formulation. Always consult with a healthcare professional before starting supplementation.
FAQs
1. Is it safe to take Fisetin Powder daily?
In general, Fisetin is safe within the recommended dosage range. However, consult a healthcare provider before daily use, especially at higher doses or for long periods of time.
2. Are there any side effects of Fisetin Powder?
Potential side effects include gastrointestinal upset, allergic reactions, and interactions with certain medications. Consult a healthcare professional before starting to take Fisetin supplements.
3. Does Fisetin Powder interact with medications?
Fisetin may interact with medications that are metabolized by liver enzymes or blood thinners. Consult a healthcare provider before combining it with other medications.
4. Can Fisetin Powder be used for skin care?
Fisetin has antioxidant properties that may improve skin health by reducing signs of aging and preventing skin damage..
Fisetin Powder Bulk Supply
We understand the demands of the anti-aging and skincare industries, where ingredient purity defines the final product's success. As a dedicated Fisetin manufacturer, we provide high-stability bulk powder specifically formulated for premium supplements and dermo-cosmetic applications. Our facility is backed by a full suite of global quality certifications, ensuring every batch meets the rigorous safety standards your brand requires. Whether you need OEM manufacturing for a new longevity line or a consistent wholesale supplier for your current production, we offer the technical expertise and scale to help you grow. Reach out to discuss how our Fisetin can elevate your formulations at info@btncbio.com.















